Kemi

Ibuprofen smeltepunkt

07. december 2021 af Hans12333 - Niveau: A-niveau

Hvorfor har racemisk ibuprofen RS-ibuprofen, højere smeltepunkt end de rene former? (s-ibuprofen og R-Ibuprofen)?


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Svar #1
19. december 2021 af Christianfslag

Af hvad jeg kunne finde vil

"The melting point of the racemic conglomerate is always lower than the pure enantiomer. Addition of a small amount of one enantiomer to the racemic compound increases the melting point."

Kilde: Racemic mixture.


Brugbart svar (0)

Svar #2
19. december 2021 af Heptan

Læs også længere nede:

"Racemic compound (sometimes true racemate)

Molecules have a higher affinity to the opposite enantiomer than to the same enantiomer, the substance forms a single crystalline phase in which the two enantiomers are present in an ordered 1:1 ratio in the elementary cell. By addition of small amount of one enantiomer to the racemic compound, the melting point decreases. But the pure enantiomer can have higher or lower melting point than the racemic compound."


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